Our integrated structural biology team is skilled and experienced in protein science, biophysics, and structural biology. In addition to providing structure-guided information on target engagement using x-ray crystallography or cryo-EM, our team offers biophysical capabilities for kinetic profiling and MOA studies.
Charles River is equipped to help you discover initial hit ID matter and then progress into the hit expansion phase of your research, offering various routes for fragment screening such as surface plasmon resonance (SPR), 19F nuclear magnetic resonance (NMR), and access to structure-based fragment screening using XCHEM services.
Contact a member of our team to discuss how we can support and accelerate your research goals.