Laboratory Sciences

Quality, scientific integrity, and regulatory compliance are key considerations when selecting an outsourcing partner. Charles River balances these values within tight timelines to deliver comprehensive laboratory services from early screening through preclinical and clinical support. Our global facilities provide complete outsourcing or supplementary resources to meet your specific requirements.

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Bioanalytical Services

Bioanalytical services span discovery through clinical development, offering GLP/GCP-compliant support for PK, immunogenicity, and biomarker studies. Expertise across modalities ensures high-quality, decision-enabling data delivered with speed and precision.

DMPK/ADME

From early screening to IND-enabling studies, DMPK services help predict how compounds are absorbed, distributed, metabolized, and excreted. Integrated in vitro and in vivo platforms support regulatory submissions and de-risk development.

Molecular Biology Services

Molecular biology capabilities support gene and cell therapy, biologics, and vaccine development with assay development, biodistribution, and transgene analysis. These services integrate seamlessly with bioanalytical and safety programs to streamline workflows.

Biomarker Testing

End-to-end biomarker services include discovery, validation, and analysis using multi-omics, flow cytometry, and gene expression platforms, enabling translational insights and regulatory-aligned decision-making from discovery through the clinic.

Immunology Testing

Immunology testing spans in vitro, ex vivo, and in vivo models to support immuno-oncology, inflammation, infectious disease, and vaccine programs. A broad platform suite delivers early immune insights and clinical biomarker support.

Pharmaceutical Formulation Development Services

Formulation experts design stable, bioavailable drug products and develop robust analytical methods to support CMC and regulatory needs. Available services include preformulation, 5-batch analysis, and stability testing to ensure product integrity.

Clinical Kitting Services

Clinical kitting services streamline sample collection and logistics for global trials, ensuring compliance and reducing delays. Customized kits, labels, and documentation are tailored to each protocol for seamless execution.

BCS Classification for Biowaivers

Using solubility and permeability data, compounds are classified under the Biopharmaceutics Classification System (BCS) to support biowaiver strategies. This approach helps reduce clinical burden and accelerate regulatory pathways for oral drugs.

Bioanalysis Platforms and Technologies

A comprehensive suite of platforms, including LC-MS/MS, ligand binding, flow cytometry, qPCR, and NanoString, supports bioanalysis across all phases. Validated, 21 CFR Part 11-compliant systems deliver reliable data for PK, immunogenicity, and biomarker studies.
 
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Unlock Your Study Insights in Real-Time.
Apollo™ Makes It Accessible.

You can access and share study-related insights in a secure environment while uncovering a new world of speed and accessibility.

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Preclinical CRO services for your Cell and Gene Therapy Safety Assessment program and beyond. Accelerate your program with expert guidance and an innovative portfolio of cell and gene therapy services and products at Charles River.

Cell and Gene Therapy Services and Products

Our comprehensive portfolio of preclinical CRO services provides the cell and gene therapy services and products, scientific, and regulatory experts to fully support your integrated program from start to finish.

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Immunology Services

Mitigate risk with early, actionable immunology data. Immunological processes play a role in most cell interactions and diseases across all systems. From target engagement and mechanism of action, to efficacy and prediction of adverse immune reactions, immunology assays deliver data that reduces your risk of failing late

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Genetic Toxicology Services

With a vast range of assays offered, we develop custom testing strategies for our clients to meet the unique requirements of their chemicals and drugs.

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CEO Jim Foster Reflects on his Remarkable 50 years at Charles River
Foster has seen it all - from the shift toward new approach methodologies, through mergers and sales and public offerings, to shaping the future of Charles River's culture. Listen now to hear how it all started, how we got here, and where we are heading in the future.
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