Spontaneously Hypertensive (SHR) Rat Details
Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure. Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.
LOCATION: Kingston
UNIT: K83
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Spontaneously Hypertensive (SHR) Rat Details
Okamoto, Kyoto School of Medicine, 1963, from outbred Wistar Kyoto male with marked elevation of blood pressure mated to female with slightly elevated blood pressure. Brother x sister mating with continued selection for spontaneous hypertension was then started. To NIH in 1966 from Okamoto at F13. To Charles River from NIH in 1973 at F32.
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Please email us at [email protected] to request a health report for this model.
For additional information, including pricing details, please visit the SHR rat page on the Vital River Laboratories website.
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Technical Resources
- Guidebook
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Baseline Colony Data
- Biochemistry and Hematology for SHR Rat Colonies in North American for January 2010 – December 2011
- Pulse Pressure for SHR/NCrl Rat Colony Fed 5L79 Diet (January – June 2007)
- Blood Pressure for Female SHR/NCrl Rat Colony (Female Data Set 1: February - June 2007)
- Blood Pressure for Male SHR/NCrl Rat Colony (Male Data Set 3: Male Data Set 1 & 2 combined)
- Blood Pressure for Male SHR/NCrl Rat Colony (Male Data Set 2: January - June 2007)
- Blood Pressure for Male SHR/NCrl Rat Colony (Male Data Set 1: March - June 2006)
- Blood Pressure Characterization of Hypertensive and Control Rats for Cardiovascular Studies
Advancing Preclinical Research with the Rat Model
This presentation will explore how the unique physiological characteristics of rats provide translational value across multiple therapeutic areas and best practices for husbandry that optimizes both welfare and experimental reproducibility. Watch Webinar Replay