Explore the Sherbrooke, Canada Site
This purpose-built toxicology facility has been in operation since 2009. In 2016, partnership established with the Molecular Imaging Center of Sherbrooke’s university teaching hospital, Centre Hospitalier Universitaire de Sherbrooke (CHUS), allowing imaging of small and large animals (MRI/MRS) in support of toxicology studies.
Laboratories and Facilities
- GLP and non-GLP study conduct
- Species: mouse, rat, rabbit, dog, minipig, large animals
- Standard and specialized routes of administration
- 12,263 square meters/132,000 square feet
- 24-hour security and fire monitoring
- 51 animal rooms
- On-site surgical suite
- Laboratories
- Analytical chemistry
- Test article formulation
- Necropsy
- Immunology
- Clinical pathology
About Sherbrooke, Canada
-
Service Areas/Study Types
- Toxicology
- Exploratory NGLP toxicology
- Acute, subchronic, chronic and carcinogenicity
- Standard and specialty routes of administration
- Immunotoxicology
- Immunogenicity
- Pharmacokinetics
- Non-GLP imaging (in partnership with the CHUS)
- Anatomical, functional and diffusion magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS)
- Whole-body imaging in small animals with positron emission tomography (PET) cameras, coupled to computed tomography (CT)
- Small animal single photon emission computed tomography (SPECT), autoradiography, optical imaging, bioluminescence and fluorescence imaging
- Radiochemistry laboratory and two cyclotrons (19 and 24 MeV)
- Toxicology
-
Compliance, Certifications, Accreditations and Professional Affiliations
Charles River’s Sherbrooke facility operates in compliance with the requirements of the following regulatory agencies or accredited organizations:
- Standards Council of Canada (SCC)
- Organization for Economic Co-operation and Development (OECD)
- U.S. Food and Drug Administration (FDA)
- U.S. Environmental Protection Agency (EPA)
- Japanese Ministry of Health, Labor and Welfare (JMHLW)
- European Medicines Agency (EMA)
- Canadian Council on Animal Care (CCAC)
- Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC International)
Quality and Process Initiatives
- Exceptional recruitment and training
- All SOPs shared with Senneville
- All data servers located in Senneville with redundancy
- QA specifically audits for consistency with the Senneville facility
Humane Care Initiative
Charles River is a worldwide leader in the humane care of laboratory animals. We work hand-in-hand with the scientific community to understand how living conditions, handling procedures and stress play an important role in the quality and efficiency of research.
Have questions for our scientists or want more information on how we can support your program?