The Disruptors: Innovation in Drug Discovery

At Charles River, we are passionate about our role in improving the quality of people’s lives. In this mini documentary, we highlight three patients and the pioneers working to expand knowledge and conduct novel research to unlock the secrets of the brain and the neurodegenerative process to develop the much-needed therapies of tomorrow.

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Conversations in Science with Those Leading the Way

We are living at a watershed moment in therapeutic discovery and development. It’s a time of great promise and hope, even with the most intractable diseases facing humanity. At this pivotal time, we pause to celebrate the work of our partners and engage in meaningful conversation about the current state and future of scientific innovation and its impact on human health.

 

Head shot of Rich Horgan.


Rich Horgan

Get a behind-the-scenes glimpse at how Rich and his team at Cure Rare Disease are developing customized, novel rare disease therapies that are as personalized as the people they are designed to treat.
Meet Rich

 

 


Wise Young

Take a closer look at how Dr. Wise Young and his team at W.M. Keck Center for Collaborative Neuroscience are bringing effective treatments to people with spinal cord injury.
Meet Wise

Head shot of Dr. Wise Young in front of a map graphic.

 

 

Head shot of Valerie Estess


Valerie Estess

Discover how close collaboration, strategic partnerships, and a personalized approach to drug development is propelling Valerie, and her team at Project ALS, closer to the first effective ALS treatment.
Meet Valerie

 

 


Aled Edwards

Find out how Aled, his team at M4K Pharma, and their novel open science business model are helping to seed global research for rare childhood diseases.
Meet Aled

Head shot of Aled Edwards

 

 

Head shot of Mark Kotter


Mark Kotter

Discover how Mark’s work in combining synthetic and stem cell biology provides stable supplies of human cell types for research and drug discovery.
Meet Mark

 

 


Ignacio Muñoz-Sanjuán

Through his drug discovery work at CHDI Foundation, a nonprofit organization, Ignacio fuels his motivation to uncover potential treatments and an eventual cure for this crippling transgenerational disease.
Meet Ignacio

Head shot of Ignacio Muñoz-Sanjuán

 

 

Head shot of Sanath Ramesh


Sanath Ramesh

Sanath was determined to track down the resources needed to repurpose a drug for his son Raghav's ultra-rare disease. Find out how his repurposed drug platform is now giving hope to other rare disease patients.
Meet Sanath