We invite you to explore the following collection of materials that describe research we have conducted at the Worcester Facility.
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Discovery Bioanalysis
- Blog: Bioassays for Checkpoint Inhibitors
- Poster: A Simple, Effective Method for Quantitative Analysis of the Biomarker Norepinephrine in Human Plasma by LC-MS/MS
- Poster: A Simple, Rapid Method for Simultaneously Quantitative Analysis of Glutathione and Glutathione Disulfide in Rat Biofluid and Tissue Samples
- Product/Service Material: Overview and Specifications of Non-GLP, Research Grade Assays
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ADME/DMPK
- Technical Sheet: In Vitro ADME Assays: Aqueous Solubility
- Poster: A 10-Point Time Course Pharmacokinetic Study Collected from a Single Mouse by use of the Mitra Microsampling Devices
- Poster: Characterization of a Rapid and Sensitive Method for Determination of Melanin Binding by Drugs (Parent and Metabolite)
- Poster: Use of Co-Spikes and Compound Cassetting to Assess Functional Integrity of Caco-2 Monolayers and Increase Throughput
- Poster: Use of Ultracentrifugation to Determine Protein Binding of Compounds Unstable in Matrix
- Poster: Using Statistical Analyses to Demonstrate Equivalency Between Automated and Manual Processes to Deliver High Quality In Vitro ADME
- Webinar: Enabling DMPK Science Delivering In Vitro ADME Even Faster
- Poster: Development of GyroLab-based in vitro immunoassays to detect pre-existing antibodies against AAV
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In Vivo Pharmacology – Oncology
- Blog: Cell Population Analysis as a Biomarker
- Blog: Making Mice a Bit Human
- Blog: Profiling Immune Subsets of Syngeneic Mouse Models
- Poster: Laminar wash AUTO system: a reliable walk-away sample preparation solution for better TILs recovery without centrifugation
- Poster: Laminar Wash™ Technology: Scalable Next Generation Platform for Pan Applications and Assay Standardization
- Poster: NCG/CRL As a Novel Humanized Mouse Model for Preclinical Oncology Studies: Immunophenotypic Characterization and Performance Monitoring
- Video Interview: Flow Cytometry in Mouse Model Development: An Interview with Christoph Eberle and Steve Festin
- Video Interview: Humanized Mice for Immuno-Oncology
- Video Interview: Is The Answer to an Effective Cancer Drug in our Gut
- Webinar: Immunophenotyping? Get Better Cell Recovery, Without the Centrifuge
- Webinar: Flow Cytometry Protocols Without Centrifugation – Towards Standardizing Flow Cytometry Sample Preparation Protocols
- Tools
Worcester Facility at a Glance Sheet
Our facility in Worcester, MA, is focused on non-GLP pharmacokinetics/pharmacodynamics (PK/PD), bioanalytical testing services, in vitro ADME, and oncology pharmacology models for the biotechnology and pharmaceutical industries.
Learn more about the Worcester facility