Vital Science™ Vault
In case you missed it, you can browse five season’s worth of archived episodes of Vital Science touching on drug discovery and development, rare disease, patient advocacy, and more.
Season 5
Episode 10:
FOX G1: A Mom’s Mission
Nasha Fitter, co-founder and CEO of the FOXG1 Research Foundation, joins us to discuss her personal connection to this ultra-rare disease, current research into potential treatments, and how you can support their mission and goals.
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Episode 09:
Cure EB: Healing the Wounds
Sharmila Nikapota of Cure EB joins us to discuss her daughter Sohana’s experience living with Epidermolysis Bullosa, the challenges of caring for her, and how Cure EB aims to help people living with this genetic skin condition.
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Episode 08:
Clear Scientific: Combatting Drug Overdose from Methamphetamine, Fentanyl, and Polydrug
Clear Scientific’s Mitch Zakin and Winston Henderson discuss a revolutionary new treatment that can help stimulant users free themselves from the effects of drug misuse and addiction.
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This bonus episode focuses on the voice of current perception of NAMs, the convergence of science and tech, alternative methods in regulatory, and the road ahead for therapeutic developers.
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Episode 07:
Mission Therapeutics: Inhibiting DUBs to Halt Diseases
Sarah Almond of Mission Therapeutics joins us to discuss deubiquitinating enzymes, how they influence therapeutic development for neurodegenerative conditions, and their future contributions to drug discovery.
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Episode 06:
Cure Rare Disease: Continuing a Legacy
Rich Horgan from Cure Rare Disease joins us to explore the lasting impact his brother Terry’s fight with Duchenne Muscular Dystrophy is affecting treatment research into this condition and other rare diseases.
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Episode 05:
H-Guard®: Improving Physical and Mental Health
Dr. Andy Herbert, co-founder of Invizius, joins us to discuss a new dialysis treatment that aims to improve the quality of life for patients suffering from chronic kidney disease.
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Episode 04:
Checking Vitals: The Disruptors
Join hosts Gina Mullane and Todd Poley as we relive some of the most memorable stories from 2023.
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Episode 03:
TREND: The Online Community Making a Difference
Maria Picone joins us to discuss her TREND Community online platform and how it uses collaboration from caregivers to advance scientific research in the field of rare disease.
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Episode 02:
Strength in Numbers
We’re joined by Bo Bigelow to discuss how his daughter’s diagnosis drove him to not only find answers for her condition but give others a platform to share their experiences with ultra-rare disease.
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Episode 01:
Emily Whitehead: Pioneer and Hero
Emily and Tom Whitehead discuss the experimental CAR-T therapy that saved Emily’s life and the Foundation that aims to do the same for pediatric cancer patients today.
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Season 4
Episode 10:
Modernizing Drug Development
Michael Templin from the Scientific Advisory Services team joins us for a discussion on the FDA Modernization Act 2.0 and how it’ll impact the development of biosimilars.
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Episode 09:
SCA3: A Family Affair
Greg Klassen joins us for a discussion on his personal battle with spinocerebellar ataxia 3 (SCA3) and what’s being done to develop a treatment for this neuromuscular disease.
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Episode 08:
Moving FAST to Treat Angelman Syndrome
Jennifer Panagoulias joins us to discuss how the Foundation for Angelman Syndrome Therapeutics (FAST) is working towards a treatment for this neurogenetic disease.
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Episode 07:
Free for Life: The Story of n-Lorem Foundation
Dr. Stanley Crooke joins us for a look at n-Lorem foundation and how they’re able to offer free, lifetime treatments for patients of ultra-rare diseases.
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Episode 06:
Evie’s Story Revisited
Evie and her mom Lindsey join us for a special look at Evie’s journey with hypophosphatasia (HPP) and what she hopes to achieve in the future.
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Episode 05:
Neurogenesis: Regenerating Hope
Dr. Wise Young joins us for a look at the future of treatment for spinal cord injuries and how neurogenesis can affect them.
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Episode 04:
AviadoBio: Bold and Courageous
AviadoBio CEO Lisa Deschamps discusses the unique approach her team is taking to deliver a therapeutic for frontotemporal dementia and other neurodegenerative diseases.
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Episode 03:
Checking Vitals
Gina Mullane and Todd Poley get together to discuss some of the memorable moments and clips from 2022.
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Episode 02:
A Father’s Race Against Time
Terry Priovolakis joins us to discuss the Cure SPG50 Foundation and their efforts to develop a treatment for his son and others affected by this ultra-rare disease.
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Episode 01:
Project ALS: Fueled by Love
Valerie Estess joins us to discuss the research efforts of Project ALS and what lies ahead.
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Season 3
Episode 10:
Logica™: Drug Discovery Made Smarter
Find out how Logica™ combines AI capabilities with data generating power to reinvent drug discovery.
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Episode 09:
Retrogenix: The Screen Door of Drug Development
Tune in to hear about the Retrogenix screening library and how developers use it to gain confidence when developing safe and effective drugs.
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Episode 08:
Open Science: The Parallel Universe
Aled Edwards discusses the concept of “open science” and how it can accelerate drug development.
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Episode 07:
(Re)programming Stem Cells for Drug Development
Mark Kotter, Founder and CEO of bit.bio, discusses technology to “reprogram” stem cells.
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Episode 06:
Are We One Shot Away?
Imagine a novel gene therapy treatment that can give drug-resistant focal epilepsy patients a better quality of life.
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Episode 04:
From Humble Beginnings to Potential Treatment for ALS
The co-founders and CEOs of Amylyx Pharmaceuticals return to discuss their latest new drug application for the treatment of ALS.
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Episode 03:
Donors: The Unsung Heroes Advancing Science
How can human cells and tissues contribute to the development of next-generation therapies? Learn more about the critical role donors play in the future of therapeutic development.
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Episode 02:
Can MILs Strike a Killer Blow to Cancer?
Join us as we explore a possible novel treatment to knock out previously untreatable cancers.
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Episode 01:
A Synergistic Approach to Treating Huntington’s Disease
Ignacio Muñoz-Sanjuan joins us for an in-depth look at research into Huntington’s disease.
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Season 2
Episode 11:
Drug Repurposing - Opening Treatments
One father’s quest to find a cure leads to a treatment pathway for others.
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Episode 10:
Drug Repurposing: Standing on the Shoulders of Giants
Drug hunters share how they reinvent approved drugs to get a head start towards treating patients.
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Episode 09:
Can a Repurposed Drug Be the Answer?
Dr. David Fajgenbaum shares how repurposed drugs saved his life and their potential to save others, including COVID-19 patients.
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Episode 08:
The Life (Saving) Blood of Horseshoe Crabs
Our panel explores the vital role horseshoe crabs play in bacterial endotoxin testing and the ongoing battle to preserve the population.
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Episode 07:
3D Cell Models: A Blueprint for Drug Development
How are 3D cell models changing our ability to create more effective therapies? Our panel of scientific experts discuss.
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Episode 06:
Driving Drug Development with CRISPR/Cas9
Dr. David Fischer joins our panel to discuss the evolution, application, and potential of CRISPR/Cas9 gene editing technology.
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Episode 05:
Get the Series Recap: Vaccines
In this brief recap, our hosts Gina Mullane and Chris Garcia discuss topics covered in our series on vaccines.
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Episode 04:
COVID-19 Vaccines – Behind the Scenes
Dr. Sarah Gould returns to provide an update on the development of a vaccine for COVID-19 and what lies ahead.
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Episode 03:
Beyond the Headlines: Understanding Accelerated Vaccines
Distinguished scientist Dr. Lauren Black discusses a “weight-of-evidence” approach to accelerated vaccine development and approvals.
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Episode 02:
A Formidable Defense Against Infectious Diseases
Dr. Christina Satterwhite delves into the immune system and how vaccines target harmful pathogens.
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Episode 01:
Infectious Disease and The Rise of Vaccines
Dr. Sarah Gould explains how infectious disease spurred the discovery, and subsequent evolution, of vaccines.
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Season 1
Episode 10:
Two in the Same
Two sisters share their experience with clinical trials for cystic fibrosis.
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Episode 09:
New Lease on Life
A dual role in medical device gives hope to one unique patient.
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Episode 07:
Uncommon Bond
Twins are forever connected in their fight against a rare disease.
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Episode 06:
Humble Beginnings
Two students, a dorm room, and a “crazy idea” to help patients.
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Episode 05:
An Angel's Determination
A personal transformation from veterinarian to rare disease advocate.
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Episode 04:
Turning Point
How an unexpected challenge changed one employee's career path forever.
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Episode 03:
A Toxigenic Situation
A microbiologist affected by mold fights for children’s health in South Carolina.
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Episode 02:
The Pathway
Mila’s story for customized medicine paves the way for other children.
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Episode 01:
Being The First
From diagnosis to experimental genetic treatment, this is Mila's story.
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Episode 00:
This is Vital Science™
Join us as we explore the motivation and personal connection to the life sciences.
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