SCID Hairless Outbred (SHO®) Mouse Details
The hairless SCID mouse was produced by Charles River Research Models in 2007 by intercrossing the Crl:HA-Prkdcscid and Crl:SKH1-Hrhr stocks. The resulting animals are homozyogous for the Prkdcscid and the Hrhr mutations and thus exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and are also hairless.
LOCATION: Raleigh
UNIT: R16I
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Immunodeficient Model Selection Poster
Compare immune cell deficits (T/B/NK), engraftment applications, and practical study considerations (e.g., leakiness and radiation tolerance) side-by-side across multiple immunodeficient mouse and rat models. Download Poster
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Charles River offers a range of translational oncology studies, including in vitro assays and in vivo models, that mirror human cancers. Whether you want to test your therapy in a cell biology assay consisting of the elements of the tumor microenvironment or in models using real patient tissue, we can help.
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Informational Resources
- Health Monitoring of Immunodeficient Rodents in Isolators in North America and Europe
- Immunodeficient Mice
Technical References
- SHO® Mouse: A Double-Homozygous SCID Hairless Outbred Model
- Characterization of a New Hairless SCID Mouse
- Trace Antibody Production by scid Mice