Webinar Overview

Drug discovery is complex and time consuming; over 95% of hits and candidates fail to make it to clinical trials. This number is likely to be even higher in neuroscience drug discovery, with many CNS diseases lacking an effective disease-modifying treatment.

Gathering high-quality data in large quantities to provide valuable insights across the early stages of drug discovery and support candidate selection, is a major hurdle for scientists. Micro-electrode array (MEA) electrophysiology uses arrays of microelectrodes to measure extracellular field potentials and enables measurement of real-time cellular activity. This enables multiplexing readouts in the same experiment to optimize data generation and can be used across the drug discovery and development process.

In this webinar, learn how:

  • MEA can be used in phenotypic screening assays, lead optimization, in vitro pharmacology profiling, and toxicology
  • MEA readouts are optimized to be biologically relevant to your drug discovery questions
  • Primary cells, human iPSC-derived cells, and ex vivo brain slices can be studied with MEA

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Webinar Presenters

Larissa Butler, PhD
Scientist II, Small Molecule Drug Discovery
Charles River

 

Amit Chouhan, PhD
Research Leader, Small Molecule Drug Discovery
Charles River

 


Additional Information