Target Discovery Services
We examine the effects of introducing shRNAs (SilenceSelect®) or full-length cDNAs (FLeXSelect®) contained within our libraries of adenoviruses into human primary cells, differentiated stem cells or cell lines. siRNA and miRNA technologies are also available for gene knockdown studies. Advanced readouts, such as high-content screening and high-throughput gene expression analysis, are used to measure the effects of knockdown and thus identify the genes that have an effect on a disease-relevant pathway.
Capabilities
- Adenoviral technology
- Advantages over conventional transfection technologies
- Human primary cell-based assays
- The most relevant systems to model human diseases
- High-content screening
- Standard cell models, human primary cells or disease-related cell lines
- Mechanism of action studies
- Application of adenoviral technology
eBook: "Translational Strategies Accelerate Drug Discovery"
This eBook focuses on translational science and discovery partnerships that advance novel therapies through a collective momentum, leveraging efficiencies in drug discovery to accelerate nonclinical research and increase clinical success.
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10 Regulatory Truths for Biotech Founders
Do not leave your breakthrough to a chance; download this complimentary infographic as a concise checklist to help you stay on track and reach your milestones.
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