MEA Testing: Bioassay to Test for Toxicity and Functionality
Ensuring safe and effective embryo development for your research lines is a necessary step for successful IVF outcomes. Our high-throughput embryology laboratory offers Mouse Embryo Assay (MEA) testing that screens media and materials for toxicity.
Mouse Embryo Assay is currently the most widely used bioassay to test for toxicity and functionality of media and materials, ensuring that the laboratory environment and equipment that come in contact with gametes or embryos are high quality and non-toxic. This increases the chance of successful IVF outcomes and validates the safety and efficacy of laboratory equipment.
We work closely with you to customize protocols and perform these assays seven days a week, enabling quick turnaround time. Our MEA testing is supported by a vast network of PhD-level scientists to ensure accurate, high quality results.
Charles River's quality and ethical standards will help you exceed all laboratory regulatory compliance requirements.
Ensure that your media and devices are clean, avoid toxicity, and enhance your IVF success rates with MEA testing.
Charles River Mouse Embryo Assay Protocols*
- Fresh or frozen one- or two-cell embryos from a cross between B6D2F1 (BDF1) and B6C3F1
- A minimum of 25 embryos per test article and 25 control embryos
- Assessment of embryos at 72, 96, or 120 hours; minimum of 80% blastocyst required for passing test
- Sample receipt seven days a week; testing typically completed within seven days
- General protocols consist of exposing test article to embryos through wash or long-term culture. Disposables, labware, or devices are typically flushed with media prior to setting up culture drops for long-term culture.
* The information above is only a guideline. Individual testing protocols can be established to suit your specific requirements.
Do You Conduct Mouse Embryo Assay Testing? We Can Help with Off-the-shelf One- or Two-cell Embryos
Charles River can support your IVF research with ready-to-go, off-the-shelf, frozen embryos generated from F1 hybrid crosses, cryopreserved at the one- or two-cell stage, and available in quantities of 10 and 20 embryos per straw.
Discuss Your Project
Why Choose Charles River for your Mouse Embryo Assay Testing and Embryo Needs?
- Expertise: Partner with our world-class PhD scientists
- Accuracy: High quality results, seven days a week
- Flexibility: Customized protocols to meet your timelines
- Quality: Trusted strategic partner with almost 90 years of experience
Frequently Asked Questions (FAQs) About Mouse Embryo Assay (MEA) Testing
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What is Mouse Embryo Assay (MEA) testing?
Mouse Embryo Assay (MEA) testing is a bioassay used to evaluate the toxicity and functionality of media and materials that come into contact with gametes or embryos. It ensures that these components are of high quality and non-toxic, increasing the chances of successful IVF outcomes.
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Why is MEA testing important for IVF laboratories?
MEA testing is crucial because it validates the safety and efficacy of the laboratory environment, equipment, and materials used in IVF procedures. It helps to prevent contamination and toxicity, which can adversely affect embryo development and success rates.
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How long does the MEA testing process take?
Our standard testing process is usually completed within seven days of receiving the sample.
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Can I customize the MEA testing protocols to suit my specific needs?
Yes, we offer customizable protocols to meet your specific requirements. Our team will work closely with you to tailor the testing process to your unique needs.
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What measures do you take to ensure the accuracy of your MEA testing?
Our MEA testing is conducted by a network of PhD-level scientists using stringent quality control measures and validated protocols to ensure high accuracy and reliability.
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What types of frozen embryos do you provide?
We offer off-the-shelf frozen embryos generated from F1 hybrid crosses, cryopreserved at the one- or two-cell stage, available in quantities of 10 and 20 embryos per straw.
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How do I get started with your MEA testing and frozen embryo services?
To get started, simply contact us to discuss your needs and schedule an initial consultation. We will guide you through the process and help you set up your customized MEA testing protocol and provide you with a detailed, transparent, competitive price quote.