Research Models & Services

In the rapidly-evolving world of biomedical science, Charles River’s comprehensive portfolio of research models and services allows us to help our clients research, discover, and develop new therapies. Our global network of commercial breeding facilities; rigorous genetic standards; and core values of animal welfare, biosecurity, and the 3Rs uniquely position us to support your specific research needs.

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animal technician wearing personal protective equipment holding a mouse at eye level

Looking for Something Else?

  • Are you a US federal government researcher? Learn about our discounted pricing under the GSA schedule.
  • Are you an NCI grantee searching for highly referenced, cost-efficient models? Learn more about our NCI Grantee Program.
  • Looking for the most efficient dosing methodology that also supports the 3Rs? Consider ALZET® Osmotic Pumps.
  • Can't find the exact match for your needs? Consider model creation services for transgenic mice and rats.
  • Any other questions? Ask our team.

lab technician holding a mouse in gloved hands

Better Science Starts with Better Care
Learn how our comprehensive programs support both animal welfare and research integrity.
Explore our commitment to the 3Rs


humanized mice are immunodeficient models used in studies for immuno-oncology and infectious disease research

Hu-Mouse™ Portfolio
As drug development for cancer and immunological diseases continue, there is a growing demand for specialized mouse models with human immune systems. Find out which humanized, study-ready models are best for your research by viewing our Hu-Mouse™ portfolio, or create your own humanized mouse model using our NCG/PBMC select humanization kit to improve your immuno-oncology studies.

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white mouse

Explore Our Global Portfolio of Preclinical Research Services
Our rigorous quality standards and attention to animal welfare uniquely position us to support your need for animal models and services, animal diagnostics, remote colony management, and turnkey vivarium space. View the video to learn more.


SRG Rat

Immunocompromised SRG Rat
The SRG rat is highly immunodeficient – lacking mature B, T, and NK cells. Combined with its larger size relative to mice, it is an ideal model for many oncology and infectious disease applications.

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Charles River Guidebook Series for colony management, genetics, diagnostics for research animals

Download the Charles River Guidebook Series
Receive essential guidance on everything from colony management to genetic testing, health surveillance, clinical signs and more.

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CRADL vivarium rental

CRADL™ Vivarium Rental
Struggling with the thought of building and managing a new vivarium? By occupying space at one of Charles River's CRADL™ facilities, you can eliminate large infrastructure costs and focus on your research. It's an ideal solution for startups looking for a lean approach to their research, and for existing pharmaceutical and biotech organizations looking to expand.

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Illustration of pipes

Choosing Wisely: The Ethics, Science, and Emotion Behind Species Selection
Sarah Gould unpacks the high-stakes, emotion-filled world of species selection—and why it’s about so much more than science. Discover how this critical choice shapes safety, speeds development, and drives innovation in today’s evolving research landscape.

Listen to the Podcast