GLP and Non-GLP Studies Conducted in Spencerville
Founded as Springborn Laboratories in 1976, Charles River acquired this facility in 2003. With approximately 285 employees, they maintain the 233,000 square foot, 93-room facility. Springborn Laboratories is FDA, EPA, USDA, AALAC, JWHLW, and EMA accredited.
285
employees
11
study directors
9
board-certified pathologists
Welcome to Apollo™
This new and secure cloud-based platform gives you real-time access to view your study data and visualize your program milestones, all in one place. Apollo™ removes barriers and empowers your safety assessment journey.
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Services and Study Types
Laboratories
- Physiochemical
- Analytical chemistry
- Test article formulation
- Clinical pathology
- Histopathology
- Necropsy
- X-ray imaging
- Physiochemical testing
- General toxicology
- Acute (eye and skin irritation, oral, dermal, and inhalation toxicity, and dermal sensitization studies)
- Subacute, subchronic, and chronic
- Standard and specialized routes of administration
- Carcinogenicity
- Transgenic studies
- Dermal toxicology
- Ocular toxicology
- Safety pharmacology (stand-alone studies or general toxicology endpoints)
- Jacketed external telemetry (JET) for cardiovascular assessments for large animals
- Respiratory pharmacology in rodents
- Functional observation battery tests
- Wound healing in rodents and large animals
- Type I and type II diabetic models in rodents and large animals
- Medical device testing
Investigational New Drug Planning Considerations
Growing pressure in the market is changing drug development, requiring researchers to accelerate early phases to create late-stage pipeline growth. Our Investigational New Drug eGuide will help you understand how and when to plan your preclinical IND-enabling studies to meet specific milestones and submit your investigational new drug application successfully and efficiently.
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Humane Care
Charles River is a worldwide leader in the humane care of laboratory animals. We work hand-in-hand with the scientific community to understand how living conditions, handling procedures, and stress play an important role in the quality and efficiency of research.