Infusion Pumps for Continuous Dosing of Laboratory Animals
ALZET Osmotic Pumps offer specific advantages over repeated animal dosing by injection or oral gavage, such as:
- Continuous delivery, eliminating peak and trough fluctuations
- Test agent effects develop fully and are easily reproduced, which is particularly advantageous for agents with short half-lives
- Reduction in animal stress that can develop from frequent handling
WEBINAR
Rethinking Animal Dosing: The Case for Implantable Infusion Systems
This webinar explores how implantable infusion systems, such as ALZET® Osmotic Pumps, offer a controlled and efficient approach to dosing.
Watch
ALZET Osmotic Pump Specifications
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ALZET Osmotic Pump Details by Study Design
There are 13 models of ALZET Osmotic Pumps in 3 physical sizes, and a variety of release rates and durations.* Dosage variability can be achieved by modifying agent concentration; duration can be extended by serial implantation of the pumps.
Pump Model Volume Duration Release Rate 1003D 100 µl 3 days 1.0 µl/hr 1007D 100 µl 1 week 0.5 µl/hr 1002 100 µl 2 weeks 0.25 µl/hr 1004 100 µl 4 weeks 0.11 µl/hr 1006 100 µl 6 weeks 0.8 µl/hr 2001D 200 µl 1 day 8.0 µl/hr 2001 200 µl 1 week 1.0 µl/hr 2002 200 µl 2 weeks 0.5 µl/hr 2004 200 µl 4 weeks 0.25 µl/hr 2006 200 µl 6 weeks 0.15 µl/hr 2ML1 2 ml 1 week 10 µl/hr 2ML2 2 ml 2 weeks 5.0 µl/hr 2ML4 2 ml 4 weeks 2.5 µl/hr * Lot-specific performance data: The nominal performance is a target for all pumps manufactured. Individual lots of pumps may vary from this target within limits. The actual pumping rate and fill volume of a particular lot (derived by statistical testing) are listed on the top of the instruction sheet included with the pumps.
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ALZET Osmotic Pump Details by Animal & Delivery Method
The minimum animal size estimates for Implantation of ALZET Osmotic Pumps are based on experience with male Sprague Dawley rats and Swiss Webster mice. When using the pumps with other strains or genders, these guidelines should be modified accordingly.
Pump Model Mice SC Mice IP Rats SC Rats IP 1003D 10 g 20 g 10 g 20 g 1007D 10 g 20 g 10 g 20 g 1002 10 g 20 g 10 g 20 g 1004 10 g 20 g 10 g 20 g 1006 10 g 20 g 10 g 20 g 2001D 10 g 20 g 10 g 20 g 2001 10 g 20 g 10 g 20 g 2002 20 g N/A 20 g 150 g 2004 20 g N/A 20 g 150 g 2006 20 g N/A 20 g 150 g 2ML1 N/A N/A 150 g 300 g 2ML2 N/A N/A 150 g 300 g 2ML4 N/A N/A 150 g 300 g SC = subcutaneous; IP = intraperitoneal
Associated ALZET Osmotic Pump Products
ALZET Video Resources
Videos detailing the technology, benefits, and applications of ALZET Osmotic Pumps may be accessed through our secure portal, The Source℠.
- ALZET Osmotic Pumps Mechanism Video
- ALZET Osmotic Pumps Surgical Implantation Techniques Video
- Lab Animals with ALZET Osmotic Pumps Video
ALZET® is a registered trademark of ALZET® LLC.