A One-Stop Solution for All Your Cell Culture Samples
The Celsis Adapt™ Sample Concentrator is the latest addition to the Celsis® rapid microbiological detection platform, designed specifically to remove non-microbial sample components, such as cellular debris found in cell and gene therapies, as well as preservatives and antimicrobial agents in cosmetics and personal care samples. Compatible with both the Celsis Accel® and Celsis Advance II™ instruments, the Celsis Adapt is the perfect accessory system to further unlock the potential of Celsis ATP-bioluminescence for cell-based therapies and faster results.
Explore the Celsis® Rapid Microbial Detection Brochure
Gain insight into Celsis® technologies, platform capabilities, implementation considerations, validation support, and microbial detection applications across a range of product types.
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Introducing the Celsis Adapt™ Sample Concentrator System
Conventional ATP-based and other rapid microbiological methods are often not capable of providing robust results due to high background which masks the signal from microbial contamination. By removing the cellular debris and thus reducing the non-microbial ATP background, ATP-bioluminescence results can be achieved much sooner.
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Product Specifications
Size (Height x Width x Depth): 13.9 in x 11.5 in x 6.2 in / 35.3 cm x 29.2 cm x 15.7 cm Weight: 8.8 lbs / 4.0 kg Electrical Requirements: Supply: 100-240VAC, 1.5A, 50-60 Hz
Operating: 12VDC, 3AMaximum Sample Volume: 10 mL Software Compatibility: Operated with on-board firmware
Pre-programmed protocolsCelsis® Instrument Compatibility: Celsis Advance II™
Celsis Accel®
Celsis® Reagent Kits Available:Celsis Adapt™ Cell 100 Kit
Celsis Adapt™ Express 100 Kit -
Product Codes
Product Code Celsis Adapt™ Sample Concentrator
On-board firmware
Power Supply with Type B, C, and G Regional Adapters
Washing Solution Adapter
Tubing Line & ClipAD9000 Celsis Adapt™ Cell 100 Kit
Celsis Adapt™ Cell Reagents
Celsis Adapt™ Concentrating Solution, Sterile x 3 cans
Celsis Adapt™ Tips, 0.2 µm , Sterile x 40 tips
Celsis Adapt™ Maintenance Tip x 1 tipAD1420 Celsis Advance II™ Instrument
Celsis® Advance II.im software
USB-serial cable
Power supply
Cuvette rack
Reagent rackC7456004
Validate Sterility in Cell Therapies
Discover how ATP-bioluminescence helps overcome validation challenges in cell-based products. Insights from Labors LS and Charles River.
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How the Celsis Adapt™ Sample Concentrator Works
Samples are prepared according to traditional sample preparation methods through membrane filtration or direct inoculation followed by a reduced incubation time of 3-7 days. The samples are then drawn through the Celsis Adapt hollow fiber sampling tip, capturing bacterial, fungal, and yeast contaminants, while removing cells, cellular debris, and other components.
The Celsis Adapt concentrating solution then flushes and concentrates any captured contamination into a sample vessel to a volume of 300-500 μL in less than 45 minutes.
This sample can then be moved to the Celsis Advance II or Celsis Accel unit for rapid contamination detection results in less than one hour.
The additional sample preparation procedure using the Celsis Adapt adds less than 45 minutes to the overall assay time. The concentrated sample allows for faster detection as it has been cleaned of background interference and cellular components.
Rapid Sterility Testing for Advanced Therapies
Align quality control with pace of innovation. By reducing time-to-release, you can minimize cold chain stress, preserve product integrity, and ensure timely delivery of life-saving treatments without compromising compliance. Think beyond your current release process and leverage a method that supports both regulatory expectations and patient needs.
Rapid Sterility Testing for Cell and Gene Therapies
Implementing rapid sterility testing solutions for your cell and gene therapy enables faster product release without compromising safety and quality. Learn how to streamline your QC processes to support timely delivery of personalized therapies and ensure regulatory readiness.
Regulatory Changes: USP 73 & 1071 Updates at a Glance
The latest chapters of USP <73> and <1071> introduce key updates impacting sterility testing and rapid microbiological methods (RMMs). Our expert guide breaks down what’s new and how Celsis® can help you stay compliant and efficient.
Explore the Guide
Frequently Asked Questions (FAQs) about Celsis Adapt Sample Concentrator
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What does the Celsis Adapt do?
The Celsis Adapt Sample Concentrator instrument cleans and concentrates samples, expanding the vast range of products that can be tested on the Celsis system or reducing the overall time-to-result. Utilizing this instrument with one of our two new reagents kits allows for Celsis ATP-bioluminescence to be used for cell-containing pharmaceutical products, such as in-process cell culture or cellular therapies.
For cosmetic and personal care manufacturers, it can be used to concentrate samples and remove background signal to speed up the time to results from 18-24 hours down to just 8 hours.
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What is the Celsis Adapt compatible with?
The Celsis Adapt, in conjunction with one of our two new industry tailored reagent kits (Celsis Adapt Cell for Pharma & Biotech or Celsis Adapt Express for Cosmetics & Personal Care), is compatible with both of our current Celsis luminometers, the Celsis Advance II, and the smaller Celsis Accel.
While other suppliers require you to purchase separate instruments, placing more burden on your laboratory to implement, learn, and use a separate rapid microbiological method, we provide a companion instrument to the current Celsis platform. This reduces the need on your laboratory to validate and maintain an entirely separate rapid microbiological method. To learn more about how the Celsis Adapt can help unlock critical rapid microbial detection applications for your lab, such as for cell culture samples or short-shelf-life product testing, contact our technical experts. -
How long does the assay take?
The Celsis Adapt Sample Concentrator workflow requires less than one hour of sample preparation before samples are ready to be analyzed on a Celsis luminometer, which has an analysis time of less than one hour. In practical applications, the overall assay takes less than two hours, with much of that time being hands-off automated instrument testing. For more information regarding overall assay times for the incubation or enrichment period prior to sample preparation and analysis, please see our corresponding application pages for more details.